Ketorolac Tromethamine is a human prescription drug labeled by 'Direct Rx'. National Drug Code (NDC) number for Ketorolac Tromethamine is 72189-335. This drug is available in dosage form of Solution. The names of the active, medicinal ingredients in Ketorolac Tromethamine drug includes Ketorolac Tromethamine - 5 mg/mL . The currest status of Ketorolac Tromethamine drug is Active.

Ketorolac tromethamine ketorolac tromethamine sodium chloride water benzalkonium chloride sodium hydroxide ketorolac tromethamine ketorolac octoxynol-40 hydrochloric acid edetate disodium

Before you use ketorolac tromethamine ophthalmic solution 0.5% for the first time: 1.check to make sure that the tamper evident ring between the bottle and the cap is not broken ( see figure a). if the tamper evident ring is broken or missing, contact your pharmacist. [img-fig-a] 2.tear off the tamper evident ring ( see figure b). [img-fig-b] 3.to open the bottle, remove the cap by turning it in the counterclockwise direction ( see figure c). [img-fig-c] this instructions for use has been approved by the u.s. food and drug administration. rev.10/2021

Ketorolac tromethamine ophthalmic solution 0.5% is indicated for the temporary relief of ocular itching due to seasonal allergic conjunctivitis. ketorolac tromethamine ophthalmic solution 0.5% is also indicated for the treatment of postoperative inflammation in patients who have undergone cataract extraction.

Ketorolac tromethamine ophthalmic solution 0.5% is a member of the pyrrolo-­pyrrole group of nonsteroidal anti-inflammatory drugs (nsaids) for ophthalmic use. its chemical name is (±)-5-benzoyl-2,3-dihydro-1h pyrrolizine-1-carboxylic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) and it has the following structure: ketorolac tromethamine ophthalmic solution 0.5% is supplied as a sterile isotonic aqueous 0.5% solution, with a ph of 7.4. ketorolac tromethamine ophthalmic solution 0.5% is a racemic mixture of r-(+) and s-(-)- ketorolac tromethamine. ketorolac tromethamine may exist in three crystal forms. all forms are equally soluble in water. the pka of ketorolac is 3.5. this white to off-white crystalline substance discolors on prolonged exposure to light. the molecular weight of ketorolac tromethamine is 376.41. the osmolality of ketorolac tromethamine ophthalmic solution 0.5% is 290 mosmol/kg. each ml of ketorolac tromethamine ophthalmic solution contains: active: ketorolac tromethamine 0.5%. preservative: benzalkonium chloride 0.01%. inactives: edetate disodium 0.1%; octoxynol 40; water for injection; sodium chloride; hydrochloric acid and/or sodium hydroxide to adjust the ph.

Two controlled clinical studies showed that ketorolac tromethamine ophthalmic solution was significantly more effective than its vehicle in relieving ocular itching caused by seasonal allergic conjunctivitis. two controlled clinical studies showed that patients treated for two weeks with ketorolac tromethamine ophthalmic solution were less likely to have measurable signs of inflammation (cell and flare) than patients treated with its vehicle. results from clinical studies indicate that ketorolac tromethamine has no significant effect upon intraocular pressure; however, changes in intraocular pressure may occur following cataract surgery.

Ketorolac tromethamine ophthalmic solution 0.5% is supplied sterile, in white opaque ldpe bottles with white opaque ldpe nozzles with hdpe grey caps as follows. 3 ml in 5 ml bottle ndc 42571-137-31 5 ml in 5 ml bottle ndc 42571-137-25 10 ml in 10 ml bottle ndc 42571-137-26 storage: store at 20° to 25°c (68° to 77°f) [see usp controlled room temperature].

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