Potassium Acetate is a human prescription drug labeled by 'Hospira, Inc.'. National Drug Code (NDC) number for Potassium Acetate is 0409-8183. This drug is available in dosage form of Injection, Solution, Concentrate. The names of the active, medicinal ingredients in Potassium Acetate drug includes Potassium Acetate - 3.93 g/20mL . The currest status of Potassium Acetate drug is Active.

Potassium acetate potassium acetate potassium acetate potassium cation water acetic acid

Indications and usage potassium acetate injection, usp, 40 meq is indicated as a source of potassium, for the addition to large volume intravenous fluids, to prevent or correct hypokalemia in patients with restricted or no oral intake. it is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions.

Warnings potassium acetate injection, usp, 40 meq must be diluted before use. to avoid potassium intoxication, infuse potassium-containing solutions slowly. potassium replacement therapy should be monitored whenever possible by continuous or serial electrocardiography (ecg). serum potassium levels are not necessarily dependable indicators of tissue potassium levels. solutions which contain potassium ions should be used with great care, if at all, in patients with hyperkalemia, severe renal failure and in conditions in which potassium retention is present. in patients with diminished renal function, administration of solutions containing potassium ions may result in potassium retention. solutions containing acetate ions should be used with great care in patients with metabolic or respiratory alkalosis. acetate should be administered with great care in those conditions in which there is an increased level or an impaired utilization of this ion, such as severe hepatic insufficiency. warni Read more...

Dosage and administration potassium acetate injection, usp, 40 meq is administered intravenously only after dilution in a larger volume of fluid . the dose and rate of administration are dependent upon the individual needs of the patient. ecg and serum potassium should be monitored as a guide to dosage. using aseptic technique, all or part of the contents of one or more vials may be added to other intravenous fluids to provide any desired number of milliequivalents (meq) of potassium (k + ) with an equal number of milliequivalents of acetate (ch 3 coo − ). maximum infusion rate: the infusion rate should not exceed 1 meq/kg/hr. normal daily requirements: newborn: 2-6 meq/kg/24 hr. children: 2-3 meq/kg/24 hr. adult: 40-80 meq/24 hr. intraosseous infusion can be an alternate route for drug administration when intravenous access is not readily available. parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever sol Read more...

Contraindications potassium administration is contraindicated in patients with severe renal insufficiency or adrenal insufficiency and in diseases where high potassium levels may be encountered.

Adverse reactions adverse reactions involve the possibility of potassium intoxication. the signs and symptoms of potassium intoxication include paresthesias of the extremities, flaccid paralysis, listlessness, mental confusion, weakness and heaviness of the legs, hypotension, cardiac arrhythmias, heart block, electrocardiographic abnormalities such as disappearance of p waves, spreading and slurring of the qrs complex with development of a biphasic curve and cardiac arrest. (see warnings and precautions .)

Pregnancy animal reproduction studies have not been conducted with potassium acetate. it is also not known whether potassium acetate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. potassium acetate should be given to a pregnant woman only if clearly needed.

Pediatric use: the safety and effectiveness of potassium acetate have been established in pediatric patients.

Geriatric use: an evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. in general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. potassium ions are known to be substantially excreted by the kidney, and the risk of toxic reactions may be greater in patients with impaired renal function. because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.

Overdosage in the event of overdosage, discontinue infusion containing potassium acetate immediately and institute corrective therapy as indicated to reduce elevated serum potassium levels and restore acid-base balance if necessary. (see warnings , precautions , and adverse reactions .)

Description potassium acetate injection, usp, 40 meq (2 meq/ml) is a sterile, nonpyrogenic, concentrated solution of potassium acetate in water for injection. the solution is administered after dilution by the intravenous route as an electrolyte replenisher. it must not be administered undiluted. each 20 ml vial contains 3.93 g of potassium acetate which provides 40 meq each of potassium (k + ) and acetate (ch 3 coo − ). it contains no bacteriostat, antimicrobial agent or added buffer. may contain acetic acid for ph adjustment. ph 6.2 (5.5 to 8.0). the osmolar concentration is 4 mosmol/ml (calc.). the solution is intended as an alternative to potassium chloride to provide potassium ion (k + ) for addition to large volume infusion fluids for intravenous use. potassium acetate, usp is chemically designated ch 3 cook, colorless crystals or white crystalline powder very soluble in water. the semi-rigid vial is fabricated from a specially formulated polyolefin. it is a copolymer of ethylene and propylene. the safety of the plastic has been confirmed by tests in animals according to usp biological standards for plastic containers. the container requires no vapor barrier to maintain the proper drug concentration.

Clinical pharmacology as the principal cation of the intracellular fluid, potassium plays an important role in fluid and electrolyte balance. the normal potassium concentration in the intracellular fluid compartment is about 160 meq/liter. the normal serum potassium range is 3.5 to 5.0 meq/liter. the kidney normally regulates potassium balance but does not conserve potassium as well or as promptly as it conserves sodium. the daily turnover of potassium in the normal adult averages 50 to 150 meq (milliequivalents) and represents 1.5 to 5% of the total potassium content of the body. acetate (ch 3 coo − ), a source of hydrogen ion acceptors, is an alternate source of bicarbonate (hco 3 − ) by metabolic conversion in the liver. this has been shown to proceed readily, even in the presence of severe liver disease.

How supplied potassium acetate injection, usp is supplied as follows: unit of sale concentration each ndc 0409-8183-01 carton of 25 40 meq/20 ml (2 meq/ml) ndc 0409-8183-11 single-dose fliptop vial each container is partially filled to provide air space for complete vacuum withdrawal of the contents into the intravenous container. store at 20 to 25°c (68 to 77°f). [see usp controlled room temperature.] distributed by hospira, inc., lake forest, il 60045 usa lab-0901-2.0 9/2017 logo

Principal display panel - 20 ml vial label 20 ml single-dose k + rx only potassium acetate injection, usp 40 meq/20 ml (2 meq/ml) caution: must be diluted. for intravenous use. distributed by hospira, inc., lake forest, il 60045 usa principal display panel - 20 ml vial label

Principal display panel - 20 ml vial tray 20 ml single-dose ndc 0409-8183-01 contains 25 of ndc 0409-8183-11 potassium acetate injection, usp 40 meq/20 ml (2 meq/ml) caution: must be diluted. for intravenous use. rx only hospira principal display panel - 20 ml vial tray