Potassium Chloride In Dextrose And Sodium Chloride

Dextrose, Sodium Chloride, And Potassium Chloride


B. Braun Medical Inc.
Human Prescription Drug
NDC 0264-7638
Potassium Chloride In Dextrose And Sodium Chloride also known as Dextrose, Sodium Chloride, And Potassium Chloride is a human prescription drug labeled by 'B. Braun Medical Inc.'. National Drug Code (NDC) number for Potassium Chloride In Dextrose And Sodium Chloride is 0264-7638. This drug is available in dosage form of Injection. The names of the active, medicinal ingredients in Potassium Chloride In Dextrose And Sodium Chloride drug includes Dextrose - 5 g/100mL Potassium Chloride - .3 g/100mL Sodium Chloride - .45 g/100mL . The currest status of Potassium Chloride In Dextrose And Sodium Chloride drug is Active.

Drug Information:

Drug NDC: 0264-7638
The labeler code and product code segments of the National Drug Code number, separated by a hyphen. Asterisks are no longer used or included within the product code segment to indicate certain configurations of the NDC.
Proprietary Name: Potassium Chloride In Dextrose And Sodium Chloride
Also known as the trade name. It is the name of the product chosen by the labeler.
Product Type: Human Prescription Drug
Indicates the type of product, such as Human Prescription Drug or Human OTC Drug. This data element corresponds to the “Document Type” of the SPL submission for the listing.
Non Proprietary Name: Dextrose, Sodium Chloride, And Potassium Chloride
Also known as the generic name, this is usually the active ingredient(s) of the product.
Labeler Name: B. Braun Medical Inc.
Name of Company corresponding to the labeler code segment of the ProductNDC.
Dosage Form: Injection
The translation of the DosageForm Code submitted by the firm. There is no standard, but values may include terms like `tablet` or `solution for injection`.The complete list of codes and translations can be found www.fda.gov/edrls under Structured Product Labeling Resources.
Status: Active
FDA does not review and approve unfinished products. Therefore, all products in this file are considered unapproved.
Substance Name:DEXTROSE - 5 g/100mL
POTASSIUM CHLORIDE - .3 g/100mL
SODIUM CHLORIDE - .45 g/100mL
This is the active ingredient list. Each ingredient name is the preferred term of the UNII code submitted.
Route Details:INTRAVENOUS
The translation of the Route Code submitted by the firm, indicating route of administration. The complete list of codes and translations can be found at www.fda.gov/edrls under Structured Product Labeling Resources.

Marketing Information:

An openfda section: An annotation with additional product identifiers, such as NUII and UPC, of the drug product, if available.
Marketing Category: NDA
Product types are broken down into several potential Marketing Categories, such as New Drug Application (NDA), Abbreviated New Drug Application (ANDA), BLA, OTC Monograph, or Unapproved Drug. One and only one Marketing Category may be chosen for a product, not all marketing categories are available to all product types. Currently, only final marketed product categories are included. The complete list of codes and translations can be found at www.fda.gov/edrls under Structured Product Labeling Resources.
Marketing Start Date: 17 Feb, 1988
This is the date that the labeler indicates was the start of its marketing of the drug product.
Marketing End Date: 25 Dec, 2025
This is the date the product will no longer be available on the market. If a product is no longer being manufactured, in most cases, the FDA recommends firms use the expiration date of the last lot produced as the EndMarketingDate, to reflect the potential for drug product to remain available after manufacturing has ceased. Products that are the subject of ongoing manufacturing will not ordinarily have any EndMarketingDate. Products with a value in the EndMarketingDate will be removed from the NDC Directory when the EndMarketingDate is reached.
Application Number: NDA019630
This corresponds to the NDA, ANDA, or BLA number reported by the labeler for products which have the corresponding Marketing Category designated. If the designated Marketing Category is OTC Monograph Final or OTC Monograph Not Final, then the Application number will be the CFR citation corresponding to the appropriate Monograph (e.g. “part 341”). For unapproved drugs, this field will be null.
Listing Expiration Date: 31 Dec, 2023
This is the date when the listing record will expire if not updated or certified by the firm.

OpenFDA Information:

An openfda section: An annotation with additional product identifiers, such as NUII and UPC, of the drug product, if available.
Manufacturer Name:B. Braun Medical Inc.
Name of manufacturer or company that makes this drug product, corresponding to the labeler code segment of the NDC.
RxCUI:615099
615100
615107
630796
1863605
1863973
1863975
1863988
1866190
The RxNorm Concept Unique Identifier. RxCUI is a unique number that describes a semantic concept about the drug product, including its ingredients, strength, and dose forms.
Original Packager:Yes
Whether or not the drug has been repackaged for distribution.
UNII:IY9XDZ35W2
660YQ98I10
451W47IQ8X
Unique Ingredient Identifier, which is a non-proprietary, free, unique, unambiguous, non-semantic, alphanumeric identifier based on a substance’s molecular structure and/or descriptive information.
Pharmacologic Class:Increased Large Intestinal Motility [PE]
Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]
Osmotic Activity [MoA]
Osmotic Laxative [EPC]
Potassium Compounds [CS]
Potassium Salt [EPC]
These are the reported pharmacological class categories corresponding to the SubstanceNames listed above.

Packaging Information:

Package NDCDescriptionMarketing Start DateMarketing End DateSample Available
0264-7638-0012 CONTAINER in 1 CASE (0264-7638-00) / 1000 mL in 1 CONTAINER17 Feb, 1988N/ANo
Package NDC number, known as the NDC, identifies the labeler, product, and trade package size. The first segment, the labeler code, is assigned by the FDA. Description tells the size and type of packaging in sentence form. Multilevel packages will have the descriptions concatenated together.

Product Elements:

Potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water potassium chloride in dextrose and sodium chloride dextrose, sodium chloride, and potassium chloride dextrose dextrose sodium chloride sodium cation chloride ion potassium chloride potassium cation water

Indications and Usage:

Indications and usage these intravenous solutions are indicated for use in adults and pediatric patients as sources of electrolytes, calories and water for hydration.

Warnings:

Warnings the administration of intravenous solutions can cause fluid and/or solute overload resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. the risk of dilutional states is inversely proportional to the electrolyte concentration. the risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentration. solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states in which there is sodium retention with edema. in patients with diminished renal function, administration of solutions containing sodium or potassium ions may result in sodium or potassium retention. solutions containing potassium ions should be used with great care, if at all, in patients with hyperkalemia, severe renal failure, and in conditions in which potassium retention is present
.

General Precautions:

General these solutions should be used with care in patients with hypervolemia, renal insufficiency, urinary tract obstruction, or impending or frank cardiac decompensation. extraordinary electrolyte losses such as may occur during protracted nasogastric suction, vomiting, diarrhea or gastrointestinal fistula drainage may necessitate additional electrolyte supplementation. additional essential electrolytes, minerals and vitamins should be supplied as needed. sodium-containing solutions should be administered with caution to patients receiving corticosteroids or corticotropin, or to other salt-retaining patients. care should be exercised in administering solutions containing sodium or potassium to patients with renal or cardiovascular insufficiency, with or without congestive heart failure, particularly if they are postoperative or elderly. potassium therapy should be guided primarily by serial electrocardiograms, especially in patients receiving digitalis. serum potassium levels are no
t necessarily indicative of tissue potassium levels. solutions containing potassium should be used with caution in the presence of cardiac disease, particularly when accompanied by renal disease. solutions containing dextrose should be used with caution in patients with overt or known subclinical diabetes mellitus, or carbohydrate intolerance for any reason. to minimize the risk of possible incompatibilities arising from mixing any of these solutions with other additives that may be prescribed, the final infusate should be inspected for cloudiness or precipitation immediately after mixing, prior to administration, and periodically during administration. do not use plastic containers in series connection. if administration is controlled by a pumping device, care must be taken to discontinue pumping action before the container runs dry or air embolism may result. if administration is not controlled by a pumping device, refrain from applying excessive pressure (>300mmhg) causing distortion to the container such as wringing or twisting. such handling could result in breakage of the container. these solutions are intended for intravenous administration using sterile equipment. it is recommended that intravenous administration apparatus be replaced at least once every 24 hours. use only if solution is clear and container and seals are intact.

Dosage and Administration:

Dosage and administration these solutions are for intravenous use only. dosage is to be directed by a physician and is dependent upon age, weight, clinical condition of the patient and laboratory determinations. frequent laboratory determinations and clinical evaluation are essential to monitor changes in blood glucose and electrolyte concentrations, and fluid and electrolyte balance during prolonged parenteral therapy. when a hypertonic solution is to be administered peripherally, it should be slowly infused through a small bore needle, placed well within the lumen of a large vein to minimize venous irritation. carefully avoid infiltration. usually, up to 40 meq of potassium per liter daily is sufficient to replace normal loss in adults. typical infusion rates should not exceed 10 meq per hour or 120 meq per day. pediatric patients may require 2 to 3 meq per kg of body weight daily. see warnings and precautions for pediatric use. fluid administration should be based on calculated main
tenance or replacement fluid requirements for each patient. dextrose may be administered to normal individuals at a rate of 0.5 g/kg/hour without producing glycosuria. at the maximum infusion rate of 0.8 g/kg/hour, approximately 95% of the dextrose is retained. some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Contraindications:

Contraindications these solutions are contraindicated where the administration of sodium, potassium or chloride could be clinically detrimental. solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products.

Adverse Reactions:

Adverse reactions reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. too rapid infusion of hypertonic solutions may cause local pain and venous irritation. rate of administration should be adjusted according to tolerance. use of the largest peripheral vein and a small bore needle is recommended. (see dosage and administration .) symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential. hypernatremia may be associated with edema and exacerbation of congestive heart failure due to the retention of water, resulting in an expanded extracellular fluid volume. reactions reported with the use of potassium-containing solutions include nausea, vomiting, abdominal pain and diarrhea. the signs and
symptoms of potassium intoxication include paresthesias of the extremities, areflexia, muscular or respiratory paralysis, mental confusion, weakness, hypotension, cardiac arrhythmias, heart block, electrocardiographic abnormalities and cardiac arrest. potassium deficits result in disruption of neuromuscular function, and intestinal ileus and dilatation. if infused in large amounts, chloride ions may cause a loss of bicarbonate ions, resulting in an acidifying effect. the physician should also be alert to the possibility of adverse reaction to drug additives. prescribing information for drug additives to be administered in this manner should be consulted. if an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Use in Pregnancy:

Pregnancy teratogenic effects pregnancy category c. animal reproduction studies have not been conducted with potassium chloride in dextrose and sodium chloride injections usp. it is also not known whether potassium chloride in dextrose and sodium chloride injections usp can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. potassium chloride in dextrose and sodium chloride injections usp should be given to a pregnant woman only if clearly needed.

Pediatric Use:

Pediatric use safety and effectiveness of potassium chloride in dextrose and sodium chloride injections usp in pediatric patients have not been established by adequate and well-controlled studies. however, as referenced in the medical literature, potassium chloride injection has been used to treat pediatric patients with potassium deficiency when oral replacement therapy is not feasible. for patients receiving potassium supplement at greater than maintenance rates, frequent monitoring of serum potassium levels and serial ekgs are recommended. dextrose is safe and effective for the stated indications in pediatric patients (see indications and usage ). as reported in the literature, the dosage selection and constant infusion rate of intravenous dextrose must be selected with caution in pediatric patients, particularly neonates and low birth weight infants, because of the increased risk of hyperglycemia/hypoglycemia. frequent monitoring of serum glucose concentrations is required when dex
trose is prescribed to pediatric patients, particularly neonates and low birth weight infants. in neonates or in very small infants even small volumes of fluid may affect fluid and electrolyte balance. care must be exercised in treatment of neonates, especially pre-term neonates, whose renal function may be immature and whose ability to excrete fluid and solute loads may be limited. fluid intake, urine output, and serum electrolytes should be monitored closely. see warnings and dosage and administration .

Geriatric Use:

Geriatric use clinical studies of potassium chloride in dextrose and sodium chloride injections usp did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. other reported clinical experience has not identified differences in responses between elderly and younger patients. in general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. these drugs are known to be substantially excreted by the kidney, and the risk of toxic reactions to these drugs may be greater in patients with impaired renal function. because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. see warnings .

Overdosage:

Overdosage in the event of fluid overload during parenteral therapy, reevaluate the patient's condition, and institute appropriate corrective treatment. in the event of overdosage with potassium-containing solutions, discontinue the infusion immediately and institute corrective therapy to reduce serum potassium levels. treatment of hyperkalemia includes the following: dextrose injection usp, 10% or 25%, containing 10 units of crystalline insulin per 20 grams of dextrose administered intravenously, 300 to 500 ml per hour. absorption and exchange of potassium using sodium or ammonium cycle cation exchange resin, orally and as retention enema. hemodialysis and peritoneal dialysis. the use of potassium-containing foods or medications must be eliminated. however, in cases of digitalization, too rapid a lowering of plasma potassium concentration can cause digitalis toxicity.

Description:

Description (see chart below for quantitative information.) potassium chloride in dextrose and sodium chloride injections usp are sterile, nonpyrogenic and contain no bacteriostatic or antimicrobial agents. these products are intended for intravenous administration. the formulas of the active ingredients are: ingredients molecular formula molecular weight sodium chloride usp potassium chloride usp nacl kcl 58.44 74.55 hydrous dextrose usp 198.17 composition – each 100 ml contains: solution hydrous dextrose usp sodium chloride usp potassium chloride usp concentration of electrolytes (meq/liter) calories per liter calculated osmolarity mosmol/liter ph sodium potassium chloride water for injection usp qs 0.15% potassium chloride in 5% dextrose and 0.20% sodium chloride injection usp 5 g 0.2 g 0.15 g 34 20 54 170 360 4.4 (3.5–6.5) 0.15% potassium chloride in 5% dextrose and 0.33% sodium chloride injection usp 5 g 0.33 g 0.15 g 56 20 76 170 405 4.4 (3.5–6.5) 0.075% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp 5 g 0.45 g 0.075 g 77 10 87 170 425 4.4 (3.5–6.5) 0.15% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp 5 g 0.45 g 0.15 g 77 20 97 170 445 4.4 (3.5–6.5) 0.22% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp 5 g 0.45 g 0.22 g 77 30 107 170 465 4.4 (3.5–6.5) 0.30% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp 5 g 0.45 g 0.3 g 77 40 117 170 490 4.4 (3.5–6.5) 0.15% potassium chloride in 5% dextrose and 0.9% sodium chloride injection usp 5 g 0.9 g 0.15 g 154 20 174 170 600 4.4 (3.5–6.5) not made with natural rubber latex, pvc or dehp. the plastic container is made from a multilayered film specifically developed for parenteral drugs. it contains no plasticizers and exhibits virtually no leachables. the solution contact layer is a rubberized copolymer of ethylene and propylene. the container is nontoxic and biologically inert. the container-solution unit is a closed system and is not dependent upon entry of external air during administration. the container is overwrapped to provide protection from the physical environment and to provide an additional moisture barrier when necessary. addition of medication should be accomplished using complete aseptic technique. the closure system has two ports; the one for the administration set has a tamper evident plastic protector and the other is a medication addition site. refer to the directions for use of the container. chemical structure

Clinical Pharmacology:

Clinical pharmacology these intravenous solutions provide electrolytes and calories, and are a source of water for hydration. they are capable of inducing diuresis depending on the clinical condition of the patient. sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. sodium is also associated with chloride and bicarbonate in the regulation of the acid-base equilibrium of body fluid. potassium, the principal cation of intracellular fluid, participates in carbohydrate utilization and protein synthesis, and is critical in the regulation of nerve conduction and muscle contraction, particularly in the heart. chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration. dextrose provides a source of calories. dextrose is readily metabolized, may decrease loss
es of body protein and nitrogen, promotes glycogen deposition and decreases or prevents ketosis if sufficient doses are provided.

Carcinogenesis and Mutagenesis and Impairment of Fertility:

Carcinogenesis, mutagenesis, impairment of fertility studies with potassium chloride in dextrose and sodium chloride injections usp have not been performed to evaluate carcinogenic potential, mutagenic potential, or effects on fertility.

How Supplied:

How supplied potassium chloride in dextrose and sodium chloride injections usp are supplied in excel ® containers. the 1000 ml containers are packaged 12 per case and the 250 ml containers are packaged 24 per case. canada din ndc ref size 0.15% potassium chloride in 5% dextrose and 0.20% sodium chloride injection usp (20 meq k + /liter) 01931598 0264-7645-00 l6450 1000 ml 0264-7645-20 l6452 250 ml 0.15% potassium chloride in 5% dextrose and 0.33% sodium chloride injection usp (20 meq k + /liter) 01931601 0264-7655-00 l6550 1000 ml 0.075% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp (10 meq k + /liter) 0264-7634-00 l6340 1000 ml 0.15% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp (20 meq k + /liter) 01931547 0264-7635-00 l6350 1000 ml 0.22% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp (30 meq k + /liter) 0264-7636-00 l6360 1000 ml 0.30% potassium chloride in 5% dextrose and 0.45% sodium chloride inj
ection usp (40 meq k + /liter) 01931571 0264-7638-00 l6380 1000 ml 0.15% potassium chloride in 5% dextrose and 0.9% sodium chloride injection usp (20 meq k + /liter) 01931644 0264-7652-00 l6520 1000 ml exposure of pharmaceutical products to heat should be minimized. avoid excessive heat. protect from freezing. it is recommended that the product be stored at room temperature (25°c). storage in automated dispensing machines: brief exposure up to 2 weeks to ultraviolet or fluorescent light does not adversely affect the product labeling legibility; prolonged exposure can cause fading of the red label. rotate stock frequently.

Spl Patient Package Insert:

Directions for use of excel® container caution: do not use plastic containers in series connection. to open tear overwrap down at notch and remove solution container. check for minute leaks by squeezing solution container firmly. if leaks are found, discard solution as sterility may be impaired. if supplemental medication is desired, follow directions below before preparing for administration. note : before use, perform the following checks: inspect each container. read the label. ensure solution is the one ordered and is within the expiration date. invert container and carefully inspect the solution in good light for cloudiness, haze, or particulate matter. any container which is suspect should not be used. use only if solution is clear and container and seals are intact. preparation for administration remove plastic protector from sterile set port at bottom of container. attach administration set. refer to complete directions accompanying set. to add medication warning: some addit
ives may be incompatible. to add medication before solution administration prepare medication site. using syringe with 18–22 gauge needle, puncture medication port and inner diaphragm and inject. squeeze and tap ports while ports are upright and mix solution and medication thoroughly. to add medication during solution administration close clamp on the set. prepare medication site. using syringe with 18–22 gauge needle of appropriate length (at least 5/8 inch), puncture resealable medication port and inner diaphragm and inject. remove container from iv pole and/or turn to an upright position. evacuate both ports by tapping and squeezing them while container is in the upright position. mix solution and medication thoroughly. return container to in use position and continue administration.

Package Label Principal Display Panel:

Principal display panel - 1000 ml container label 0.075% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp ref l6340 ndc 0264-7634-00 1000 ml excel ® container 10 meq k + /liter y94-003-346 ld-258-3 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.45 g; potassium chloride usp 0.075 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 425 mosmol/liter, hypertonic electrolytes (meq/liter): na + 77; k + 10; cl – 87 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 y94-003-285 ld-166-3 exp lot recycle 7 1000 ml_container label_l6340

Principal display panel - 1000 ml container label 0.15% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp ref l6350 ndc 0264-7635-00 din 01931547 1000 ml excel ® container 20 meq k+/liter y94-003-347 ld-265-4 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.45 g; potassium chloride usp 0.15 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 445 mosmol/liter, hypertonic electrolytes (meq/liter): na + 77; k + 20; cl – 97 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 in canada, distributed by: b. braun of canada, ltd. scarborough, ontario m1h 2w4 y94-003-299 ld-158-4 exp lot recycle 7 1000 ml_container label_l6350

Principal display panel - 1000 ml container label 0.22% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp ref l6360 ndc 0264-7636-00 1000 ml excel® container 30 meq k+/liter y94-003-348 ld-266-3 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.45 g; potassium chloride usp 0.22 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 465 mosmol/liter, hypertonic electrolytes (meq/liter): na + 77; k + 30; cl – 107 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 y94-003-283 ld-157-3 exp lot recycle 7 1000 ml_container label_l6360

Principal display panel - 1000 ml container label 0.30% potassium chloride in 5% dextrose and 0.45% sodium chloride injection usp ref l6380 ndc 0264-7638-00 din 01931571 1000 ml excel® container 40 meq k+/liter y94-003-349 ld-274-3 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.45 g; potassium chloride usp 0.3 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 490 mosmol/liter, hypertonic electrolytes (meq/liter): na + 77; k + 40; cl – 117 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings : some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 in canada, distributed by: b. braun of canada, ltd. scarborough, ontario m1h 2w4 y94-003-281 ld-156-3 exp lot recycle 7 1000 ml_container label_l6380

Principal display panel - 1000 ml container label 0.15% potassium chloride in 5% dextrose and 0.20% sodium chloride injection usp ref l6450 ndc 0264-7645-00 din 01931598 1000 ml excel ® container 20 meq k+/liter y94-003-350 ld-506-2 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.2 g; potassium chloride usp 0.15 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 360 mosmol/liter, hypertonic electrolytes (meq/liter): na + 34; k + 20; cl – 54 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 in canada, distributed by: b. braun of canada, ltd. scarborough, ontario m1h 2w4 y94-003-279 ld-163-3 exp lot recycle 7 1000 ml_container label_l6450

Principal display panel - 250 ml container label 0.15% potassium chloride in 5% dextrose and 0.20% sodium chloride injection usp ref l6452 ndc 0264-7645-20 din 01931598 250 ml excel ® container 20 meq k + /liter y94-003-274 ld-267-2 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.2 g; potassium chloride usp 0.15 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 360 mosmol/liter, hypertonic electrolytes (meq/liter): na + 34; k + 20; cl – 54 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 in canada, distributed by: b. braun of canada, ltd. scarborough, ontario m1h 2w4 y94-003-273 ld-162-3 exp lot recycle symbol 250 ml_container label_l6452

Principal display panel - 1000 ml container label 0.15% potassium chloride in 5% dextrose and 0.9% sodium chloride injection usp ref l6520 ndc 0264-7652-00 din 01931644 1000 ml excel ® container 20 meq k + /liter y94-003-351 ld-504-2 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.9 g; potassium chloride usp 0.15 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 600 mosmol/liter, hypertonic electrolytes (meq/liter): na + 154; k + 20; cl – 174 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 in canada, distributed by: b. braun of canada, ltd. scarborough, ontario m1h 2w4 y94-003-275 ld-155-3 exp lot recycle 7 1000 ml_container label_l6520

Principal display panel - 1000 ml container label 0.15% potassium chloride in 5% dextrose and 0.33% sodium chloride injection usp ref l6550 ndc 0264-7655-00 din 01931601 1000 ml excel ® container 20 meq k + /liter y94-003-352 ld-505-2 each 100 ml contains: hydrous dextrose usp 5 g; sodium chloride usp 0.33 g; potassium chloride usp 0.15 g; water for injection usp qs ph: 4.4 (3.5-6.5); calc. osmolarity: 405 mosmol/liter, hypertonic electrolytes (meq/liter): na + 56; k + 20; cl – 76 sterile, nonpyrogenic. single dose container. do not use in series connection. for intravenous use only. use only if solution is clear and container and seals are intact. warnings: some additives may be incompatible. consult with pharmacist. when introducing additives, use aseptic techniques. mix thoroughly. do not store. recommended storage: room temperature (25°c). avoid excessive heat. protect from freezing. see package insert. do not remove overwrap until ready for use. after removing the overwrap, check for minute leaks by squeezing container firmly. if leaks are found, discard solution as sterility may be impaired. not made with natural rubber latex, pvc or dehp. rx only excel is a registered trademark of b. braun medical inc. b. braun medical inc. bethlehem, pa 18018-3524 usa 1-800-227-2862 in canada, distributed by: b. braun of canada, ltd. scarborough, ontario m1h 2w4 y94-003-277 ld-159-3 exp lot recycle symbol 1000 ml_container label_l6550


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